Archive for November, 2013

Krill oil use

Posted: November 27, 2013 in Medicine raw material
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Krill oil is oil from a tiny, shrimp-like animal. Baleen whales, mantas, and bang sharks eat primarily krill. In Norwegian, the chat “krill” agency “whale food.” People abstract the oil from krill, abode it in capsules, and use it for medicine. Some cast name krill oil articles announce that they use Antarctic krill. This usually refers to the breed of krill alleged Euphausia superba.

Krill oil is acclimated for affection disease, top levels of assertive claret fats (triglycerides), top cholesterol, top claret pressure, stroke, cancer, osteoarthritis, depression, premenstrual affection (PMS), and aching menstrual periods.

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What is Eldecalcitol?

Posted: November 22, 2013 in Medicine raw material
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Eldecalcitol [1α,25-dihydroxy-2β-(3-hydroxypropyloxy)-vitamin D₃] is an alternation of 1α,25-dihydroxyvitamin D₃ [1,25(OH)₂D₃], address a hydroxypropyloxy balance at the 2β position. Eldecalcitol shows stronger furnishings than alfacalcidol to access cartilage mineral body and abate cartilage absorption markers in osteoporotic patients, and articulate once-daily 0.75 μg eldecalcitol bargain vertebral breach accident by 26% compared to 1.0 μg alfacalcidol in a 3-year randomized, double-blind, active-comparator analytic trial. The aftereffect of eldecalcitol on vertebral breach accident was abiding throughout the 3-year abstraction period, and the anniversary accident of vertebral breach during the third year was decidedly lower with eldecalcitol rather than with alfacalcidol analysis (3.9% vs 7.0%, respectively). Eldecalcitol aswell bargain the accident of wrist fractures by 71% compared to alfacalcidol. Eldecalcitol is able-bodied acceptable and is not associated with austere ancillary furnishings including abiding hypercalcemia. Eldecalcitol was accustomed for the analysis of osteoporosis in Japan in 2011.

CAS:209216-23-9

Molecular formula:C12H17N5O4

Molecular weight:295.29448

Boiling Point:734.2 °C at 760 mmHg

Flash Point:397.9 °C

Appearance:White crystalline powder

Product description:Entecavir hydrate is an articulate antiviral biologic acclimated in the analysis of hepatitis B infection. Entecavir hydrate is a nucleoside analog (more specifically, a guanine analogue) that inhibits about-face transcription, DNA archetype and archetype in the viral archetype process. Entecavir hydrate is added alive than antecedent agents acclimated to amusement hepatitis B (lamivudine and adefovir). Entecavir hydrate is aswell adumbrated for the analysis of abiding hepatitis B in adults with HIV/AIDS infection. However, Entecavir hydrate is not alive adjoin HIV.

CAS:183319-69-9

Molecular formula:C22H23N3O4.HCl

Molecular weight:429.9

Appearance: Off-white to pale yellow powder

Solubility: Soluble in DMSO at 18 mg/mL with warming; very poorly soluble in ethanol; very poorly soluble in water; maximum solubility in plain water is estimated to be about 5-20 µM; buffers, serum, or other additives may increase or decrease the aqueous solubility.

Storage: Store at -20° C

Application: An HER-1/EGFR tyrosine kinase inhibitor

Usage:

drug used to treat non-small cell lung cancer, pancreatic cancer and several other types of cancer. It is a tyrosine kinase inhibitor, which acts on the epidermal growth factor receptor

Product description:Erlotinib hydrochloride is an HER-1/EGFR tyrosine kinase inhibitora, a small molecule inhibitor of the human epidermal growth factor receptor (HER-1/EGFR) tyrosine kinase. Overexpression of the EGFR is present in many carcinomas, and inhibition of the activating kinase by Erlotinib provides a chemical intervention upon these systems.